Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion.

We have investigated the effect of redox changes in vivo on the differentiation of two human myeloid cell lines, HL-60 and KG-1. The glutathione-depleting agent diethyl maleate (DEM) prevented the development of differentiated features in response to phorbol esters, including adherence of the cells...

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Autores principales: Esposito, F, Agosti, V, Morrone, G, Morra, F, Cuomo, C, Russo, T, Venuta, S, Cimino, F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137037/
https://ncbi.nlm.nih.gov/pubmed/7519845
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