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Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.
We have examined the role of glutathione synthesis and intracellular glutathione content in the formation of leukotriene C (LTC) by mouse peritoneal macrophages. For this purpose, we utilized the drug buthionine sulfoximine (BSO), a specific inhibitor of glutathione synthesis. Thirty minutes after t...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6113592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2532 |
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