Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.

We have examined the role of glutathione synthesis and intracellular glutathione content in the formation of leukotriene C (LTC) by mouse peritoneal macrophages. For this purpose, we utilized the drug buthionine sulfoximine (BSO), a specific inhibitor of glutathione synthesis. Thirty minutes after t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Rouzer, C A, Scott, W A, Griffith, O W, Hamill, A L, Cohn, Z A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6113592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2532
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