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Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.

We have examined the role of glutathione synthesis and intracellular glutathione content in the formation of leukotriene C (LTC) by mouse peritoneal macrophages. For this purpose, we utilized the drug buthionine sulfoximine (BSO), a specific inhibitor of glutathione synthesis. Thirty minutes after t...

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Bibliografische gegevens
Hoofdauteurs: Rouzer, C A, Scott, W A, Griffith, O W, Hamill, A L, Cohn, Z A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1981
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC319382/
https://ncbi.nlm.nih.gov/pubmed/6113592
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