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Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent

Phenethyl isothiocyanate (PEITC) is a naturally occurring electrophile which depletes intracellular glutathione (GSH) levels and triggers accumulation of reactive oxygen species (ROS). PEITC is of considerable interest as a potential chemopreventive/chemotherapeutic agent, and in this work, we have...

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Detalhes bibliográficos
Main Authors: Syed Alwi, Sharifah S., Cavell, Breeze E., Donlevy, Alison, Packham, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535168/
https://ncbi.nlm.nih.gov/pubmed/22351438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0329-3
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