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Inhibition of Mitochondrial Respiration and Rapid Depletion of Mitochondrial Glutathione by β-Phenethyl Isothiocyanate: Mechanisms for Anti-Leukemia Activity

AIMS: β-Phenethyl isothiocyanate (PEITC) is a natural product with potent anticancer activity against human leukemia cells including drug-resistant primary leukemia cells from patients. This study aimed at investigating the key mechanisms that contribute to the potent anti-leukemia activity of PEITC...

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Detalhes bibliográficos
Main Authors: Chen, Gang, Chen, Zhao, Hu, Yumin, Huang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201634/
https://ncbi.nlm.nih.gov/pubmed/21827296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4170
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