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Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness
The concept of robustness in biology has gained much attention recently, but a mechanistic understanding of how genetic networks regulate phenotypic variation has remained elusive. One approach to understand the genetic architecture of variability has been to analyze dispensable gene deletions in mo...
Tallennettuna:
| Julkaisussa: | Mol Syst Biol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BlackWell Publishing Ltd
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332149/ https://ncbi.nlm.nih.gov/pubmed/25609648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145264 |
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