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Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness
The concept of robustness in biology has gained much attention recently, but a mechanistic understanding of how genetic networks regulate phenotypic variation has remained elusive. One approach to understand the genetic architecture of variability has been to analyze dispensable gene deletions in mo...
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| Veröffentlicht in: | Mol Syst Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332149/ https://ncbi.nlm.nih.gov/pubmed/25609648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145264 |
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