Laddar...

Inhibition of a DNA Polymerase from Bacillus subtilis by Hydroxyphenylazopyrimidines

The antimicrobial agent, 6-(p-hydroxyphenylazo)-uracil, specifically inhibits DNA polymerase III of Bacillus subtilis with a K(i) of less than 1 μM. The inhibition requires prior reduction of the drug, is reversible, and is competitive with dGTP. High amounts of dATP prevent inhibition by the closel...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Gass, Kenneth B., Low, Robert L., Cozzarelli, Nicholas R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 1973
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4630611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.1.103
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!