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PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation

Cellular senescence is a stable state of proliferative arrest that provides a barrier against malignant transformation and contributes to the antitumor activity of certain chemotherapies. Unexpectedly, we found that the expression of proto-oncogene PIM-1, which can promote tumorigenesis, is induced...

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Publicat a:Aging Cell
Autors principals: Jin, Bo, Wang, Yu, Wu, Chen Lin, Liu, Kai Yu, Chen, Hao, Mao, Ze Bin
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331745/
https://ncbi.nlm.nih.gov/pubmed/25040935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12249
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