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PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation
Cellular senescence is a stable state of proliferative arrest that provides a barrier against malignant transformation and contributes to the antitumor activity of certain chemotherapies. Unexpectedly, we found that the expression of proto-oncogene PIM-1, which can promote tumorigenesis, is induced...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331745/ https://ncbi.nlm.nih.gov/pubmed/25040935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12249 |
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