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Positively Charged Amino Acids at the SNAP-25 C Terminus Determine Fusion Rates, Fusion Pore Properties, and Energetics of Tight SNARE Complex Zippering

SNAP-25 is a Q-SNARE protein mediating exocytosis of neurosecretory vesicles including chromaffin granules. Previous results with a SNAP-25 construct lacking the nine C terminal residues (SNAP-25Δ9) showed changed fusion pore properties (Fang et al., 2008), suggesting a model for fusion pore mechani...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Fang, Qinghua, Zhao, Ying, Herbst, Adam Drew, Kim, Brian N., Lindau, Manfred
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331636/
https://ncbi.nlm.nih.gov/pubmed/25698757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2905-14.2015
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