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Early etiology of Alzheimer’s disease: tipping the balance toward autophagy or endosomal dysfunction?

Alzheimer’s disease (AD) is the most common form of dementia in the elderly. This brain neuropathology is characterized by a progressive synaptic dysfunction and neuronal loss, which lead to decline in memory and other cognitive functions. Histopathologically, AD manifests via synaptic abnormalities...

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Bibliographic Details
Published in:Acta Neuropathol
Main Authors: Peric, Aleksandar, Annaert, Wim
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331606/
https://ncbi.nlm.nih.gov/pubmed/25556159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1379-7
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