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Dysfunctional autophagy in Alzheimer’s disease: pathogenic roles and therapeutic implications

Neuronal autophagy is essential for neuronal survival and the maintenance of neuronal homeostasis. Increasing evidence has implicated autophagic dysfunction in the pathogenesis of Alzheimer’s disease (AD). The mechanisms underlying autophagic failure in AD involve several steps, from autophagosome f...

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Vydáno v:Neurosci Bull
Hlavní autoři: Liang, Jun-Hua, Jia, Jian-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562662/
https://ncbi.nlm.nih.gov/pubmed/24610177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1418-8
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