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Early etiology of Alzheimer’s disease: tipping the balance toward autophagy or endosomal dysfunction?
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. This brain neuropathology is characterized by a progressive synaptic dysfunction and neuronal loss, which lead to decline in memory and other cognitive functions. Histopathologically, AD manifests via synaptic abnormalities...
Gespeichert in:
| Veröffentlicht in: | Acta Neuropathol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331606/ https://ncbi.nlm.nih.gov/pubmed/25556159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1379-7 |
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