Azilsartan Reduced TNF-α and IL-1β Levels, Increased IL-10 Levels and Upregulated VEGF, FGF, KGF, and TGF-α in an Oral Mucositis Model

Oral mucositis (OM) is a common complication of treatments for head and neck cancer, particularly radiotherapy with or without chemotherapy. OM is characterised by oral erythema, ulceration, and pain. The aim of this study was to evaluate the effect of azilsartan (AZT), an angiotensin II receptor an...

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Publicat a:PLoS One
Autors principals: de Araújo, Aurigena Antunes, Varela, Hugo, de Medeiros, Caroline Addison Carvalho Xavier, de Castro Brito, Gerly Anne, de Lima, Kênio Costa, de Moura, Ligia Moreno, de Araújo, Raimundo Fernandes
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331549/
https://ncbi.nlm.nih.gov/pubmed/25689279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116799
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