Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up-Regulates OPG in an Experimental Periodontitis Model

AIMS: The aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear factor κB (RANK), osteoprotegerin (OPG), cyclooxygena...

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Detalhes bibliográficos
Main Authors: de Araújo, Aurigena Antunes, Varela, Hugo, Brito, Gerly Anne de Castro, de Medeiros, Caroline Addison Carvalho Xavier, Araújo, Lorena de Souza, do Nascimento, José Heriberto Oliveira, de Araújo Júnior, Raimundo Fernandes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018354/
https://ncbi.nlm.nih.gov/pubmed/24819928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096750
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