Engineering a Fibrocartilage Spectrum Through Modulation of Aggregate Redifferentiation

Expanded costochondral cells provide a clinically relevant cell source for engineering both fibrous and hyaline articular cartilage. Expanding chondrocytes in monolayer results in a shift toward a proliferative, fibroblastic phenotype. Three-dimensional aggregate culture may, however, be used to rec...

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Udgivet i:Cell Transplant
Main Authors: Murphy, Meghan K., Masters, Taylor E., Hu, Jerry C., Athanasiou, Kyriacos A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331269/
https://ncbi.nlm.nih.gov/pubmed/24380383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368913X676204
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