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Effects of passage number and post-expansion aggregate culture on tissue engineered, self-assembled neocartilage

Chondrocyte dedifferentiation presents a major barrier in engineering functional cartilage constructs. To mitigate the effects of dedifferentiation, this study employed a post-expansion aggregate culture step to enhance the chondrogenic phenotype of passaged articular chondrocytes (ACs) before their...

Полное описание

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Библиографические подробности
Опубликовано в: :Acta Biomater
Главные авторы: Huang, Brian J., Hu, Jerry C., Athanasiou, Kyriacos A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012947/
https://ncbi.nlm.nih.gov/pubmed/27475530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.07.044
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