Combined use of chondroitinase-ABC, TGF-β1 and collagen crosslinking agent lysyl oxidase to engineer functional neotissues for fibrocartilage repair

Patients suffering from damaged or diseased fibrocartilages currently have no effective long-term treatment options. Despite their potential, engineered tissues suffer from inferior biomechanical integrity and an inability to integrate in vivo. The present study identifies a treatment regimen (inclu...

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Bibliographische Detailangaben
Hauptverfasser: Makris, Eleftherios A., MacBarb, Regina F., Paschos, Nikolaos K., Hu, Jerry C., Athanasiou, Kyriacos A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105108/
https://ncbi.nlm.nih.gov/pubmed/24840619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.04.083
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