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Relationship between in vivo degradative rates and isoelectric points of proteins.

Previous studies have shown that in mammalian cells proteins of large molecular weight are degraded more rapidly than small ones. Evidence is presented here that half-lives of proteins are also related to their isoelectric points. A double-isotope method was used to compare degradative rates of solu...

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Autors principals: Dice, J F, Goldberg, A L
Format: Artigo
Idioma:Inglês
Publicat: 1975
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC433102/
https://ncbi.nlm.nih.gov/pubmed/1060070
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