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Relationship between in vivo degradative rates and isoelectric points of proteins.

Previous studies have shown that in mammalian cells proteins of large molecular weight are degraded more rapidly than small ones. Evidence is presented here that half-lives of proteins are also related to their isoelectric points. A double-isotope method was used to compare degradative rates of solu...

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Detalhes bibliográficos
Main Authors: Dice, J F, Goldberg, A L
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433102/
https://ncbi.nlm.nih.gov/pubmed/1060070
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