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CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination
Ig heavy chain (IgH) variable region exons are assembled from V, D, and J gene segments during early B-lymphocyte differentiation. A several megabase region at the “distal” end of the mouse IgH locus (Igh) contains hundreds of V(H)s, separated by an intergenic region from Igh Ds, J(H)s, and constant...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330762/ https://ncbi.nlm.nih.gov/pubmed/25624508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424936112 |
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