Competitive protein binding assay for methotrexate.

A competitive protein binding assay has been developed for methotrexate based on the tight binding of this drug to Lactobacillus casei dihydrofolate reductase (= tetrahydrofolate dehydrogenase; 5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase; EC 1.5.1.3). Free drug may be separated from that bound to...

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Bibliografiske detaljer
Main Authors: Myers, C E, Lippman, M E, Elliot, H M, Chabner, B A
Format: Artigo
Sprog:Inglês
Udgivet: 1975
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC433061/
https://ncbi.nlm.nih.gov/pubmed/810804
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