An endotoxin-induced serum factor that causes necrosis of tumors.

In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG)-infected mice treated with endotoxin contains a substance (tumor necrosis factor; TNF) which mimics the tumor necrotic action of endotoxin itself. TNF-positive serum is...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Carswell, E A, Old, L J, Kassel, R L, Green, S, Fiore, N, Williamson, B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1975
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1103152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.9.3666
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