An endotoxin-induced serum factor that causes necrosis of tumors.

In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG)-infected mice treated with endotoxin contains a substance (tumor necrosis factor; TNF) which mimics the tumor necrotic action of endotoxin itself. TNF-positive...

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Bibliographic Details
Main Authors: Carswell, E A, Old, L J, Kassel, R L, Green, S, Fiore, N, Williamson, B
Format: Artigo
Language:Inglês
Published: 1975
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC433057/
https://ncbi.nlm.nih.gov/pubmed/1103152
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