Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor.

Mouse tumor necrosis factor (TNF) was purified from serum through a series of steps, and each step was monitored for L-cell cytotoxicity in vitro and tumor-necrotizing activity in vivo. The two activities copurified and could not be dissociated. Purified mouse TNF has a specific activity of 2.2 X 10...

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Bibliografiske detaljer
Main Authors: Haranaka, K, Carswell, E A, Williamson, B D, Prendergast, J S, Satomi, N, Old, L J
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323642/
https://ncbi.nlm.nih.gov/pubmed/3520561
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