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Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor.
Mouse tumor necrosis factor (TNF) was purified from serum through a series of steps, and each step was monitored for L-cell cytotoxicity in vitro and tumor-necrotizing activity in vivo. The two activities copurified and could not be dissociated. Purified mouse TNF has a specific activity of 2.2 X 10...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3520561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3949 |
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