Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor.

Mouse tumor necrosis factor (TNF) was purified from serum through a series of steps, and each step was monitored for L-cell cytotoxicity in vitro and tumor-necrotizing activity in vivo. The two activities copurified and could not be dissociated. Purified mouse TNF has a specific activity of 2.2 X 10...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Haranaka, K, Carswell, E A, Williamson, B D, Prendergast, J S, Satomi, N, Old, L J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3520561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3949
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