Neuroinflammation and Aβ Accumulation Linked To Systemic Inflammation Are Decreased By Genetic PKR Down-Regulation

Alzheimer's disease (AD) is a neurodegenerative disorder, marked by senile plaques composed of amyloid-β (Aβ) peptide, neurofibrillary tangles, neuronal loss and neuroinflammation. Previous works have suggested that systemic inflammation could contribute to neuroinflammation and enhanced Aβ cer...

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Publicat a:Sci Rep
Autors principals: Carret-Rebillat, Anne-Sophie, Pace, Clarisse, Gourmaud, Sarah, Ravasi, Laura, Montagne-Stora, Samantha, Longueville, Sophie, Tible, Marion, Sudol, Erika, Chang, Raymond Chuen-Chung, Paquet, Claire, Mouton-Liger, François, Hugon, Jacques
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330547/
https://ncbi.nlm.nih.gov/pubmed/25687824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08489
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