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Role of WNT16 in the Regulation of Periosteal Bone Formation in Female Mice

In this study, we evaluated the role of WNT16 in regulating bone size, an important determinant of bone strength. Mice with targeted disruption of the Wnt16 gene exhibited a 24% reduction in tibia cross-sectional area at 12 weeks of age compared with that of littermate wild-type (WT) mice. Histomorp...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Wergedal, Jon E., Kesavan, Chandrasekhar, Brommage, Robert, Das, Subhashri, Mohan, Subburaman
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330302/
https://ncbi.nlm.nih.gov/pubmed/25521583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1702
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