Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Mucus barriers lining mucosal epithelia reduce the effectiveness of nanocarrier-based mucosal drug delivery and imaging (“theranostics”). Here, we describe liposome-based mucus-penetrating particles (MPP) capable of loading hydrophilic agents, e.g., the diaCEST MRI contrast agent barbituric acid (BA...

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Библиографические подробности
Опубликовано в: :Nanomedicine
Главные авторы: Yu, Tao, Chan, Kannie W. Y., Anonuevo, Abraham, Song, Xiaolei, Schuster, Benjamin S., Chattopadhyay, Sumon, Xu, Qingguo, Oskolkov, Nikita, Patel, Himatkumar, Ensign, Laura M., van Zjil, Peter C. M., McMahon, Michael T., Hanes, Justin
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330119/
https://ncbi.nlm.nih.gov/pubmed/25461289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.09.019
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