Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Mucus barriers lining mucosal epithelia reduce the effectiveness of nanocarrier-based mucosal drug delivery and imaging (“theranostics”). Here, we describe liposome-based mucus-penetrating particles (MPP) capable of loading hydrophilic agents, e.g., the diaCEST MRI contrast agent barbituric acid (BA...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Yu, Tao, Chan, Kannie W. Y., Anonuevo, Abraham, Song, Xiaolei, Schuster, Benjamin S., Chattopadhyay, Sumon, Xu, Qingguo, Oskolkov, Nikita, Patel, Himatkumar, Ensign, Laura M., van Zjil, Peter C. M., McMahon, Michael T., Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330119/
https://ncbi.nlm.nih.gov/pubmed/25461289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.09.019
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