Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Mucus barriers lining mucosal epithelia reduce the effectiveness of nanocarrier-based mucosal drug delivery and imaging (“theranostics”). Here, we describe liposome-based mucus-penetrating particles (MPP) capable of loading hydrophilic agents, e.g., the diaCEST MRI contrast agent barbituric acid (BA...

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Gepubliceerd in:Nanomedicine
Hoofdauteurs: Yu, Tao, Chan, Kannie W. Y., Anonuevo, Abraham, Song, Xiaolei, Schuster, Benjamin S., Chattopadhyay, Sumon, Xu, Qingguo, Oskolkov, Nikita, Patel, Himatkumar, Ensign, Laura M., van Zjil, Peter C. M., McMahon, Michael T., Hanes, Justin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330119/
https://ncbi.nlm.nih.gov/pubmed/25461289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.09.019
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