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Bis(aminomethyl)phosphinic Acid, a Highly Promising Scaffold for the Development of Bacterial Urease Inhibitors

[Image: see text] Inhibitors of bacterial ureases are considered to be promising compounds in the treatment of infections caused by Helicobacter pylori in the gastric tract and/or by urealytic bacteria (e.g., Proteus species) in the urinary tract. A new, extended transition state scaffold, bis(amino...

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Publicado en:ACS Med Chem Lett
Autores principales: Macegoniuk, Katarzyna, Dziełak, Anna, Mucha, Artur, Berlicki, Łukasz
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329584/
https://ncbi.nlm.nih.gov/pubmed/25699141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500380f
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