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Relative Binding Affinities of Integrin Antagonists by Equilibrium Dialysis and Liquid Chromatography–Mass Spectrometry
[Image: see text] The integrin α(v)β(6) is a potential target for treatment of idiopathic pulmonary fibrosis (IPF). Equilibrium dialysis (ED) was investigated for its ability to report ligand binding in an α(v)β(6) inhibitor screening assay. As a preliminary experiment, an established peptidomimetic...
Zapisane w:
| Wydane w: | ACS Med Chem Lett |
|---|---|
| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2014
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329580/ https://ncbi.nlm.nih.gov/pubmed/25699153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500395v |
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