Relative Binding Affinities of Integrin Antagonists by Equilibrium Dialysis and Liquid Chromatography–Mass Spectrometry

[Image: see text] The integrin α(v)β(6) is a potential target for treatment of idiopathic pulmonary fibrosis (IPF). Equilibrium dialysis (ED) was investigated for its ability to report ligand binding in an α(v)β(6) inhibitor screening assay. As a preliminary experiment, an established peptidomimetic...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Med Chem Lett
Hlavní autoři: Tipping, William J., Tshuma, Nkazimulo, Adams, James, Haywood, Harvey T., Rowedder, James E., Fray, M. Jonathan, McInally, Thomas, Macdonald, Simon J. F., Oldham, Neil J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329580/
https://ncbi.nlm.nih.gov/pubmed/25699153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500395v
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky