Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic β-adrenergic receptor stimulation

Chronic stimulation of β-adrenergic receptors (βAR) can promote survival signaling via transactivation of epidermal growth factor receptor (EGFR) but ultimately alters cardiac structure and contractility over time, in part via enhanced cytokine signaling. We hypothesized that chronic catecholamine s...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Grisanti, Laurel A., Repas, Ashley A., Talarico, Jennifer A., Gold, Jessica I., Carter, Rhonda L., Koch, Walter J., Tilley, Douglas G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Cardiovascular Neurohormonal Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329485/
https://ncbi.nlm.nih.gov/pubmed/25485901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00635.2014
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