Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic β-adrenergic receptor stimulation

Chronic stimulation of β-adrenergic receptors (βAR) can promote survival signaling via transactivation of epidermal growth factor receptor (EGFR) but ultimately alters cardiac structure and contractility over time, in part via enhanced cytokine signaling. We hypothesized that chronic catecholamine s...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Grisanti, Laurel A., Repas, Ashley A., Talarico, Jennifer A., Gold, Jessica I., Carter, Rhonda L., Koch, Walter J., Tilley, Douglas G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Cardiovascular Neurohormonal Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329485/
https://ncbi.nlm.nih.gov/pubmed/25485901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00635.2014
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