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Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells

Sodium butyrate, a histone deacetylase inhibitor, has been used to improve transgene expression in Chinese hamster ovary (CHO) cells. The current study explores the impact of butyrate treatment on heparan sulfate (HS) biosynthesis and structural composition in a recombinant CHO-S cell line expressin...

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Bibliografiske detaljer
Udgivet i:Cytotechnology
Main Authors: Datta, Payel, Yang, Bo, Linhardt, Robert J., Sharfstein, Susan T.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329296/
https://ncbi.nlm.nih.gov/pubmed/24468831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9677-9
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