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Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells

Sodium butyrate, a histone deacetylase inhibitor, has been used to improve transgene expression in Chinese hamster ovary (CHO) cells. The current study explores the impact of butyrate treatment on heparan sulfate (HS) biosynthesis and structural composition in a recombinant CHO-S cell line expressin...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Datta, Payel, Yang, Bo, Linhardt, Robert J., Sharfstein, Susan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329296/
https://ncbi.nlm.nih.gov/pubmed/24468831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9677-9
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