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Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells

Sodium butyrate, a histone deacetylase inhibitor, has been used to improve transgene expression in Chinese hamster ovary (CHO) cells. The current study explores the impact of butyrate treatment on heparan sulfate (HS) biosynthesis and structural composition in a recombinant CHO-S cell line expressin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cytotechnology
Main Authors: Datta, Payel, Yang, Bo, Linhardt, Robert J., Sharfstein, Susan T.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329296/
https://ncbi.nlm.nih.gov/pubmed/24468831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9677-9
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