Combining capillary electrophoresis and next-generation sequencing for aptamer selection

Next-generation sequencing (NGS) machines can sequence millions of DNA strands in a single run, such as oligonucleotide (oligo) libraries comprising millions to trillions of discrete oligo sequences. Capillary electrophoresis is an attractive technique to select tight binding oligos or “aptamers” be...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Riley, Kathryn R., Gagliano, Jason, Xiao, Jiajie, Libby, Kara, Saito, Shingo, Yu, Guo, Cubicciotti, Roger, Macosko, Jed, Colyer, Christa L., Guthold, Martin, Bonin, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329186/
https://ncbi.nlm.nih.gov/pubmed/25579462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-8427-y
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