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Protein-Aptamer Binding Studies Using Microchip Affinity Capillary Electrophoresis
The use of traditional capillary electrophoresis (CE) to detect weak binding complexes is problematic due to the fast-off rate resulting in the dissociation of the complex during the separation process. Additionally, proteins involved in binding interactions often nonspecifically stick to the bare-s...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529586/ https://ncbi.nlm.nih.gov/pubmed/18324729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.200700777 |
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