Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans

BACKGROUND: Little is known about the role of amino acids in cellular signaling pathways, especially as it pertains to pathways that regulate the rate of aging. However, it has been shown that methionine or tryptophan restriction extends lifespan in higher eukaryotes and increased proline or tryptop...

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Veröffentlicht in:BMC Genet
Hauptverfasser: Edwards, Clare, Canfield, John, Copes, Neil, Brito, Andres, Rehan, Muhammad, Lipps, David, Brunquell, Jessica, Westerheide, Sandy D, Bradshaw, Patrick C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328591/
https://ncbi.nlm.nih.gov/pubmed/25643626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0167-2
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