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Targeting the Adaptability of Heterogeneous Aneuploids

Aneuploid genomes, characterized by unbalanced chromosome stoichiometry (karyotype), are associated with cancer malignancy and drug-resistance of pathogenic fungi. The phenotypic diversity resulting from karyotypic diversity endows the cell population superior adaptability. We show here, using a com...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Chen, Guangbo, Mulla, Wahid A., Kucharavy, Andrei, Tsai, Hung-Ji, Rubinstein, Boris, Conkright, Juliana, McCroskey, Scott, Bradford, William D., Weems, Lauren, Haug, Jeff S., Seidel, Chris W., Berman, Judith, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4328141/
https://ncbi.nlm.nih.gov/pubmed/25679766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.026
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