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Actin Depolymerization Drives Actomyosin Ring Contraction during Budding Yeast Cytokinesis

Actin filaments and myosin-II are evolutionarily conserved force generating components of the contractile ring during cytokinesis. Here we show that in budding yeast actin filament depolymerization plays a major role in actomyosin ring constriction. Cofilin mutation or chemically stabilizing actin f...

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Detalhes bibliográficos
Main Authors: Pinto, Inês Mendes, Rubinstein, Boris, Kucharavy, Andrei, Unruh, Jay R., Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376349/
https://ncbi.nlm.nih.gov/pubmed/22698284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.04.015
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