Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response

Cancer cells exhibit modifications in nuclear architecture and transcriptional control. Tumor growth and metastasis are supported by RUNX family transcriptional scaffolding proteins, which mediate the assembly of nuclear-matrix-associated gene-regulatory hubs. We used proteomic analysis to identify...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Yang, Seungchan, Quaresma, Alexandre J. C., Nickerson, Jeffrey A., Green, Karin M., Shaffer, Scott A., Imbalzano, Anthony N., Martin-Buley, Lori A., Lian, Jane B., Stein, Janet L., van Wijnen, Andre J., Stein, Gary S.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327387/
https://ncbi.nlm.nih.gov/pubmed/25609707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.160051
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