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Hypoxia disrupts proteostasis in Caenorhabditis elegans
Oxygen is fundamentally important for cell metabolism, and as a consequence, O(2) deprivation (hypoxia) can impair many essential physiological processes. Here, we show that an active response to hypoxia disrupts cellular proteostasis – the coordination of protein synthesis, quality control, and deg...
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Publicat a: | Aging Cell |
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Autors principals: | , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
BlackWell Publishing Ltd
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326909/ https://ncbi.nlm.nih.gov/pubmed/25510338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12301 |
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