Loading...

Fasting prevents hypoxia-induced defects of proteostasis in C. elegans

Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death. We have shown that specific hypoxic conditions disrupt protein homeostasis in C. elegans, leading to protein aggregation and proteotoxicity. Here, we show that nutritional cues regulate...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Genet
Main Authors: Iranon, Nicole N., Jochim, Bailey E., Miller, Dana L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619831/
https://ncbi.nlm.nih.gov/pubmed/31246952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008242
Tags: Add Tag
No Tags, Be the first to tag this record!