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Hypoxia disrupts proteostasis in Caenorhabditis elegans

Oxygen is fundamentally important for cell metabolism, and as a consequence, O(2) deprivation (hypoxia) can impair many essential physiological processes. Here, we show that an active response to hypoxia disrupts cellular proteostasis – the coordination of protein synthesis, quality control, and deg...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Fawcett, Emily M, Hoyt, Jill M, Johnson, Jenna K, Miller, Dana L
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326909/
https://ncbi.nlm.nih.gov/pubmed/25510338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12301
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