Sulforaphane enhances progerin clearance in Hutchinson–Gilford progeria fibroblasts

Hutchinson–Gilford progeria syndrome (HGPS, OMIM 176670) is a rare multisystem childhood premature aging disorder linked to mutations in the LMNA gene. The most common HGPS mutation is found at position G608G within exon 11 of the LMNA gene. This mutation results in the deletion of 50 amino acids at...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Gabriel, Diana, Roedl, Daniela, Gordon, Leslie B, Djabali, Karima
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326906/
https://ncbi.nlm.nih.gov/pubmed/25510262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12300
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