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Sulforaphane enhances progerin clearance in Hutchinson–Gilford progeria fibroblasts
Hutchinson–Gilford progeria syndrome (HGPS, OMIM 176670) is a rare multisystem childhood premature aging disorder linked to mutations in the LMNA gene. The most common HGPS mutation is found at position G608G within exon 11 of the LMNA gene. This mutation results in the deletion of 50 amino acids at...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326906/ https://ncbi.nlm.nih.gov/pubmed/25510262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12300 |
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